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If CMS determines that a generic Part D rebatable drug that received a reduction of the rebate amount as determined under paragraph (b)(1) of this section continues to be affected by the potential drug shortage, CMS will grant a single extension of the reduction for 1 additional consecutive applicable period and reduce the total rebate amount determined under 428.201, if any is owed, as determined under paragraph (b)(2) of this section

These include individuals over 50, smokers, heavy alcohol consumers, and those diagnosed with diabetes